Instruments that Require Calibration in the Pharmaceutical Industry

There are certain instruments in the pharmaceutical industry that are critical for calibration. These instruments have a direct correlation with the quality of the end product. From ensuring the right amount of grams are put into a product to measuring the viscosity of a liquid, the calibration of all these instruments ensures no mistakes are made along the production line.


A pipette measures and transfers the accurate amount of fluid into an object or product. The slightest variation to a recipe could result in consequences to the consumer. Pipettes will need calibration for a few reasons. Depending on the liquids used in the pipette, some volatile liquids and chemicals can corrode the pipette throwing off calibration. Pipettes that are used intensively will need calibration more often than others. Further, air temperature and humidity can affect the calibration and accuracy of a pipette. Most pipettes can be calibrated every six months, but under the strict regulations of the pharmaceutical industry, quarterly calibration is recommended.

Temperature Gage

As mentioned above, the temperature in a lab can throw off the calibration of other instruments. Further, there are some materials used in the production of a product that must stay within a certain temperature, or else risk spoilage. Even a five degree difference in accuracy could risk the integrity of a product. The calibration of a temperature gage ensures that the lab stays within optimal temperatures for the safest production of pharmaceutical products.


A viscometer measures the consistency of liquids. In the pharmaceutical industry, the viscosity of a liquid can alert manufacturers to issues that they are unable to see within the product. It can also be used to decide when a batch is ready to be packaged and sold. If a viscometer is thrown off calibration, mistakes in the production of a batch could affect the well-being of the consumer. Calibration of a viscometer can determine that the viscosity of all liquids produced in a pharmaceutical lab are consistent

pH Meter

A pH Meter can be used in liquids and in some solid states. The meter is used to calculate the acidity, neutrality or alkaline measure of a product. Good practice for pH meters actually recommend that the pH meter is calibrated more than once a day in-house, and then sent out for calibration in an accredited lab every six months.